Monakhos: Created page with "PKA or Protein Kinase A 1. concentration of cAMP rises (e.g., activation of adenylate cyclase via GPCR-Gs) 2. cAMP molecules bind and release each PKA regulatory subunit. 3..."

2013-04-15T06:35:09Z

Created page with "PKA or Protein Kinase A 1. concentration of cAMP rises (e.g., activation of adenylate cyclase via GPCR-Gs) 2. cAMP molecules bind and release each PKA regulatory subunit. 3..."

New page

PKA or Protein Kinase A

1. concentration of cAMP rises (e.g., activation of adenylate cyclase via GPCR-Gs)

2. cAMP molecules bind and release each PKA regulatory subunit.

3. catalytic subunits phosphorylate Ser and Thr residues

4. PKA can directly activate CREB, which binds CRE, altering the transcription

PKA - Revision history

Monakhos: Created page with "PKA or Protein Kinase A 1. concentration of cAMP rises (e.g., activation of adenylate cyclase via GPCR-Gs) 2. cAMP molecules bind and release each PKA regulatory subunit. 3..."