Bradley Monk at 02:03, 21 March 2015

2015-03-21T02:03:45Z

← Older revision	Revision as of 19:03, 20 March 2015
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		{{Article\|Lu, Shi, Nicoll\|2009\|Cell - [http://www.sciencedirect.com/science/article/pii/S0896627309002554 FullText]\|19409270\|Subunit composition of synaptic AMPA receptors revealed by a single-cell genetic approach}}
		; FIGURE 1
		Outside-Out Patch Recordings of AMPAR-Mediated Current from CA1 Pyramidal Neurons in GluA2 KO and WT Mice
		(A) (Top) Example of the strongly inwardly rectifying I/V curve of glutamate-evoked AMPAR-mediated current, in the presence of 100 μM cyclothiazide, from acute hippocampal slice from the germline 2- to 3-week-old GluA2-KO mouse, with an RI value of 0.16. (Bottom) In a subsequent glutamate application in the same OOP, held at −60 mV, ∼99% of the current could be blocked by 100 nM PhTx-433.
		(B) Example of the linear I/V curve of glutamate-evoked current in a WT littermate, with an RI value of 0.83. (Bottom) In the same OOP, glutamate-evoked current was untouched by 100 nM PhTx-433.
		(C) Bar graph showing average RI values for each of the genotypes: GluA2-KO mice, RI = 0.12 ± 0.02 (n = 9); WT mice, RI = 0.82 ± 0.02 (n = 15).
		(D) Bar graph showing the average percent block (%) of glutamate-evoked currents by 100 nM PhTx-433 in GluA2-KO mice; average percent block is 97.9% ± 0.4% (n = 6) and, in WT mice, 0% (n = 5).
		[[Category:Synaptic Plasticity]] [[Category:Journals]]

Bradley Monk: Bradley Monk uploaded a new version of "File:Lu Nicoll 2009 F1.jpg": {{Article|Lu, Shi, Nicoll|2009|Cell - [http://www.sciencedirect.com/science/article/pii/S0896627309002554 FullText]|19409270|Subunit composition of synaptic AMPA receptors

2015-03-21T01:57:55Z

Bradley Monk uploaded a new version of "File:Lu Nicoll 2009 F1.jpg": {{Article|Lu, Shi, Nicoll|2009|Cell - [http://www.sciencedirect.com/science/article/pii/S0896627309002554 FullText]|19409270|Subunit composition of synaptic AMPA receptors

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Bradley Monk at 04:59, 2 January 2015

2015-01-02T04:59:07Z

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File:Lu Nicoll 2009 F1.jpg - Revision history

Bradley Monk at 02:03, 21 March 2015

Bradley Monk: Bradley Monk uploaded a new version of "File:Lu Nicoll 2009 F1.jpg": {{Article|Lu, Shi, Nicoll|2009|Cell - [http://www.sciencedirect.com/science/article/pii/S0896627309002554 FullText]|19409270|Subunit composition of synaptic AMPA receptors

Bradley Monk at 04:59, 2 January 2015