File:Bourne Harris 2012 F4.png - Revision history

Bradley Monk at 22:38, 2 January 2015

2015-01-02T22:38:55Z

← Older revision		Revision as of 15:38, 2 January 2015
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	{{Article\|Bourne & Harris \|2012\|~~Neuron~~ • [http://www.sciencedirect.com/science/article/pii/S0959438811001851 PDF]\|22088391\|Nanoscale analysis of structural synaptic plasticity}}		<br>
			{{Article\|Bourne & Harris \|2012\|Curr Opin Neurobiol • [http://www.sciencedirect.com/science/article/pii/S0959438811001851 PDF]\|22088391\|Nanoscale analysis of structural synaptic plasticity}}
	Dramatic structural synaptic scaling revealed by ssEM following induction of LTP by TBS in the mature hippocampus. (a) EM and (ai) reconstruction of a small thin spine (category T, head diameter <0.45 mm). (b) EM and (bi) reconstruction of a medium thin spine (category T, head diameter >0.45 mm but <0.6 mm). (c) EM and (ci) reconstruction of a mushroom spine (M, head diameter >0.6 mm). (d) Small thin spines were significantly reduced in number (P < 0.05) while (e) PSDs on all remaining spines were significantly enlarged (*P < 0.01; P < 0.05). (f) Reconstructions of control and LTP dendrites demonstrate equal summed PSD area per micron length of dendrite, despite large differences in their average synapse size and density. Scale cube = 0.5 mm on a side. (g) Average summed PSD area per micron length of dendrite is the same for dendrites across all times in the control and TBS-LTP conditions.Adapted from Bourne and Harris [4].		Dramatic structural synaptic scaling revealed by ssEM following induction of LTP by TBS in the mature hippocampus. (a) EM and (ai) reconstruction of a small thin spine (category T, head diameter <0.45 mm). (b) EM and (bi) reconstruction of a medium thin spine (category T, head diameter >0.45 mm but <0.6 mm). (c) EM and (ci) reconstruction of a mushroom spine (M, head diameter >0.6 mm). (d) Small thin spines were significantly reduced in number (P < 0.05) while (e) PSDs on all remaining spines were significantly enlarged (*P < 0.01; P < 0.05). (f) Reconstructions of control and LTP dendrites demonstrate equal summed PSD area per micron length of dendrite, despite large differences in their average synapse size and density. Scale cube = 0.5 mm on a side. (g) Average summed PSD area per micron length of dendrite is the same for dendrites across all times in the control and TBS-LTP conditions.Adapted from Bourne and Harris [4].


	[[Category:Journals]]		[[Category:Journals]]

Bradley Monk at 22:37, 2 January 2015

2015-01-02T22:37:00Z

← Older revision		Revision as of 15:37, 2 January 2015
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	{{Article\|Bourne & Harris \|2012\|Neuron • [http://www.sciencedirect.com/science/article/pii/S0959438811001851 PDF]\|22088391\|Nanoscale analysis of structural synaptic plasticity}}		{{Article\|Bourne & Harris \|2012\|Neuron • [http://www.sciencedirect.com/science/article/pii/S0959438811001851 PDF]\|22088391\|Nanoscale analysis of structural synaptic plasticity}}


	Dramatic structural synaptic scaling revealed by ssEM following induction of LTP by TBS in the mature hippocampus. (a) EM and (ai) reconstruction of a small thin spine (category T, head diameter <0.45 mm). (b) EM and (bi) reconstruction of a medium thin spine (category T, head diameter >0.45 mm but <0.6 mm). (c) EM and (ci) reconstruction of a mushroom spine (M, head diameter >0.6 mm). (d) Small thin spines were significantly reduced in number (P < 0.05) while (e) PSDs on all remaining spines were significantly enlarged (*P < 0.01; P < 0.05). (f) Reconstructions of control and LTP dendrites demonstrate equal summed PSD area per micron length of dendrite, despite large differences in their average synapse size and density. Scale cube = 0.5 mm on a side. (g) Average summed PSD area per micron length of dendrite is the same for dendrites across all times in the control and TBS-LTP conditions.Adapted from Bourne and Harris [4].		Dramatic structural synaptic scaling revealed by ssEM following induction of LTP by TBS in the mature hippocampus. (a) EM and (ai) reconstruction of a small thin spine (category T, head diameter <0.45 mm). (b) EM and (bi) reconstruction of a medium thin spine (category T, head diameter >0.45 mm but <0.6 mm). (c) EM and (ci) reconstruction of a mushroom spine (M, head diameter >0.6 mm). (d) Small thin spines were significantly reduced in number (P < 0.05) while (e) PSDs on all remaining spines were significantly enlarged (*P < 0.01; P < 0.05). (f) Reconstructions of control and LTP dendrites demonstrate equal summed PSD area per micron length of dendrite, despite large differences in their average synapse size and density. Scale cube = 0.5 mm on a side. (g) Average summed PSD area per micron length of dendrite is the same for dendrites across all times in the control and TBS-LTP conditions.Adapted from Bourne and Harris [4].

	~~<big>'''From: [http://www.sciencedirect.com/science/article/pii/S0959438811001851 Bourne & Harris (2012) Nanoscale analysis of structural synaptic plasticity]'''</big>~~

	[[Category:Journals]]		[[Category:Journals]]

Bradley Monk at 22:36, 2 January 2015

2015-01-02T22:36:37Z

← Older revision		Revision as of 15:36, 2 January 2015
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	~~Dramatic structural synaptic scaling revealed by ssEM following induction of LTP by TBS in the mature hippocampus. (a) EM and (ai) reconstruction of~~		{{Article\|Bourne & Harris \|2012\|Neuron • [http://www.sciencedirect.com/science/article/pii/S0959438811001851 PDF]\|22088391\|Nanoscale analysis of structural synaptic plasticity}}
	~~a small thin spine (category T, head diameter <0.45 mm). (b) EM and (bi) reconstruction of a medium thin spine (category T, head diameter >0.45 mm~~
	but <0.6 mm). (c) EM and (ci) reconstruction of a mushroom spine (M, head diameter >0.6 mm). (d) Small thin spines were significantly reduced in number (P < 0.05) while (e) PSDs on all remaining spines were significantly enlarged (*P < 0.01; P < 0.05). (f) Reconstructions of control and LTP
	~~dendrites demonstrate equal summed PSD area per micron length of dendrite, despite large differences in their average synapse size and density.~~
	~~Scale cube = 0.5 mm on a side. (g) Average summed PSD area per micron length of dendrite is the same for dendrites across all times in the control~~
	~~and TBS-LTP conditions.Adapted from~~ Bourne ~~and~~ Harris [~~4��~~].

	From: [http://www.sciencedirect.com/science/article/pii/S0959438811001851 Bourne & Harris (2012) Nanoscale analysis of structural synaptic plasticity]
			Dramatic structural synaptic scaling revealed by ssEM following induction of LTP by TBS in the mature hippocampus. (a) EM and (ai) reconstruction of a small thin spine (category T, head diameter <0.45 mm). (b) EM and (bi) reconstruction of a medium thin spine (category T, head diameter >0.45 mm but <0.6 mm). (c) EM and (ci) reconstruction of a mushroom spine (M, head diameter >0.6 mm). (d) Small thin spines were significantly reduced in number (P < 0.05) while (e) PSDs on all remaining spines were significantly enlarged (*P < 0.01; P < 0.05). (f) Reconstructions of control and LTP dendrites demonstrate equal summed PSD area per micron length of dendrite, despite large differences in their average synapse size and density. Scale cube = 0.5 mm on a side. (g) Average summed PSD area per micron length of dendrite is the same for dendrites across all times in the control and TBS-LTP conditions.Adapted from Bourne and Harris [4].

			<big>'''From: [http://www.sciencedirect.com/science/article/pii/S0959438811001851 Bourne & Harris (2012) Nanoscale analysis of structural synaptic plasticity]'''</big>

	[[Category:Journals]]		[[Category:Journals]]

Bradley Monk: Dramatic structural synaptic scaling revealed by ssEM following induction of LTP by TBS in the mature hippocampus. (a) EM and (ai) reconstruction of a small thin spine (category T, head diameter <0.45 mm). (b) EM and (bi) reconstruction of a medium thi...

2015-01-02T22:30:14Z

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Dramatic structural synaptic scaling revealed by ssEM following induction of LTP by TBS in the mature hippocampus. (a) EM and (ai) reconstruction of
a small thin spine (category T, head diameter <0.45 mm). (b) EM and (bi) reconstruction of a medium thin spine (category T, head diameter >0.45 mm
but <0.6 mm). (c) EM and (ci) reconstruction of a mushroom spine (M, head diameter >0.6 mm). (d) Small thin spines were significantly reduced in number (P < 0.05) while (e) PSDs on all remaining spines were significantly enlarged (**P < 0.01; *P < 0.05). (f) Reconstructions of control and LTP
dendrites demonstrate equal summed PSD area per micron length of dendrite, despite large differences in their average synapse size and density.
Scale cube = 0.5 mm on a side. (g) Average summed PSD area per micron length of dendrite is the same for dendrites across all times in the control
and TBS-LTP conditions.Adapted from Bourne and Harris [4��].

From: [http://www.sciencedirect.com/science/article/pii/S0959438811001851 Bourne & Harris (2012) Nanoscale analysis of structural synaptic plasticity]

[[Category:Journals]]